Slc15a1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Slc15a1^tm1Dgen
• Name: solute carrier family 15 (oligopeptide transporter), member 1; targeted mutation 1, Deltagen
• MGI ID: MGI:4818784
• Synonyms: Pept1^-
• Gene: Slc15a1 Location: Chr14:121697033-121742664 bp, - strand Genetic Position: Chr14, 65.26 cM, cytoband E5
• Alliance: Slc15a1^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162297
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: DNA sequence bases encoding amino acid residues 16-24 were replaced with an IRES-lacZ-neomycin selection cassette. (J:162297)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc15a1 Mutation: 42 strains or lines available

References

• Original: J:162297 Hu Y, et al., Targeted disruption of peptide transporter Pept1 gene in mice significantly reduces dipeptide absorption in intestine. Mol Pharm. 2008 Nov-Dec;5(6):1122-30
• All: 15 reference(s)