Mycl^tm1.1Rne
Targeted Allele Detail

Summary

• Symbol: Mycl^tm1.1Rne
• Name: v-myc avian myelocytomatosis viral oncogene lung carcinoma derived; targeted mutation 1.1, Robert N Eisenman
• MGI ID: MGI:4818995
• Synonyms: L-myc flox
• Gene: Mycl Location: Chr4:122889445-122896278 bp, + strand Genetic Position: Chr4, 57.36 cM
• Alliance: Mycl^tm1.1Rne page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:164343
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a loxP site upstream of the start codon, and a second loxP site just downstream of exon 3 of the v-myc myelocytomatosis viral oncogene homolog 1 (Mycl1) targeted gene. A FRT-flanked neomycin (neo) resistance cassette was located upstream of the second loxP site. Flp mediated recombination removed the neo cassette. (J:164343)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mycl Mutation: 19 strains or lines available

References

• Original: J:164343 Eisenman RN, Direct data submission 2010-08-12. MGI Direct Data Submission. 2010
• All: 4 reference(s)