Tg(THY1-tTA)177Jpj
Transgene Detail

Summary

• Symbol: Tg(THY1-tTA)177Jpj
• Name: transgene insertion 177, Jean-Pierre Julien
• MGI ID: MGI:4819013
• Synonyms: Tg(tTa)
• Transgene: Tg(THY1-tTA)177Jpj Location: unknown
• Alliance: Tg(THY1-tTA)177Jpj page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The human promoter was used to drive neuron-specific expression of the tetracycline transactivator. Three lines were established. Line 177 expresses in the nervous system with highest in the cerebral cortex and spinal cord. (J:160704)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:160704 Dequen F, et al., Reversal of neuropathy phenotypes in conditional mouse model of Charcot-Marie-Tooth disease type 2E. Hum Mol Genet. 2010 Jul 1;19(13):2616-29
• All: 1 reference(s)