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Cd4sesh
Chemically induced Allele Detail
Summary
Symbol: Cd4sesh
Name: CD4 antigen; seshat
MGI ID: MGI:4819228
Gene: Cd4  Location: Chr6:124841655-124865184 bp, - strand  Genetic Position: Chr6, 59.17 cM
Alliance: Cd4sesh page
Mutation
origin
Strain of Origin:  C57BL/6JAnu
Project Collection: APF ENU Mutagenesis
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThe mutation. in exon 4 of the gene, has been identified as a T to C transition at nucleotide position 543 of the cDNA sequence (ENSMUST00000024044), replacing valine with alanine at amino acid position 128 of the protein (p.V128A). This is the equivalent of the human p.V125A mutation. (J:104190)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cd4 Mutation:  85 strains or lines available
References
Original:  J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory