Ctcfl^tm1Vloc
Targeted Allele Detail

Summary

• Symbol: Ctcfl^tm1Vloc
• Name: CCCTC-binding factor like; targeted mutation 1, Victor Lobanenkov
• MGI ID: MGI:4819543
• Gene: Ctcfl Location: Chr2:172935402-172961318 bp, - strand Genetic Position: Chr2, 95.74 cM
• Alliance: Ctcfl^tm1Vloc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162590
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region of exon 1 through exon 8 was replaced with (5' to 3'): a loxP site, GFP, lox511 site, and FRT flanked neo cassette. The absence of transcript expression was confirmed by RT-PCR on testes extracts. (J:162590)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctcfl Mutation: 34 strains or lines available

References

• Original: J:162590 Suzuki T, et al., Expression of a testis-specific form of Gal3st1 (CST), a gene essential for spermatogenesis, is regulated by the CTCF paralogous gene BORIS. Mol Cell Biol. 2010 May;30(10):2473-84
• All: 1 reference(s)