Lin9^tm1.1Sgau
Targeted Allele Detail

Summary

• Symbol: Lin9^tm1.1Sgau
• Name: lin-9 DREAM MuvB core complex component; targeted mutation 1.1, Stefan Gaubatz
• MGI ID: MGI:4819561
• Synonyms: Lin9^fl
• Gene: Lin9 Location: Chr1:180468715-180518252 bp, + strand Genetic Position: Chr1, 84.46 cM
• Alliance: Lin9^tm1.1Sgau page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162678
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Flp mediated recombination removed the beta-geo cassette leaving exon 7 floxed. (J:162678)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lin9 Mutation: 49 strains or lines available

References

• Original: J:162678 Reichert N, et al., Lin9, a subunit of the mammalian DREAM complex, is essential for embryonic development, for survival of adult mice, and for tumor suppression. Mol Cell Biol. 2010 Jun;30(12):2896-908
• All: 3 reference(s)