Gpr17^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gpr17^tm1Dgen
• Name: G protein-coupled receptor 17; targeted mutation 1, Deltagen
• MGI ID: MGI:4819569
• Gene: Gpr17 Location: Chr18:32076050-32082689 bp, - strand Genetic Position: Chr18, 17.89 cM
• Alliance: Gpr17^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150814
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129
• Project Collection: Deltagen

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Mutation details: A lacZ-neo gene cassette interrupts 76 bp of the coding region within exon 2. Absence of transcript was confirmed by Northern blot. (J:150814)

Generation of the Gpr17^tm1Dgen allele

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr17 Mutation: 19 strains or lines available

References

• Original: J:150814 Maekawa A, et al., GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11685-90
• All: 2 reference(s)