Cimap3^tm1.1Heli
Targeted Allele Detail

Summary

• Symbol: Cimap3^tm1.1Heli
• Name: ciliary microtubule associated protein 3; targeted mutation 1.1, Heiko Lickert
• MGI ID: MGI:4819764
• Synonyms: Pifo^lacZ
• Gene: Cimap3 Location: Chr3:105904273-105921962 bp, - strand Genetic Position: Chr3, 46.47 cM, cytoband F3
• Alliance: Cimap3^tm1.1Heli page

Mutation origin

• Mouse Generated: Earliest citation of chimera generation: J:162627
• Parent Cell Line: IDG3.2 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ with a nuclear localization signal and a floxed neo cassette were inserted into exon 1b replacing all of the downstream exons. Cre mediated recombination removed the neo cassette. (J:162627)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cimap3 Mutation: 14 strains or lines available

References

• Original: J:162627 Kinzel D, et al., Pitchfork regulates primary cilia disassembly and left-right asymmetry. Dev Cell. 2010 Jul 20;19(1):66-77
• All: 2 reference(s)