Mapk1tm2Melo
Targeted Allele Detail
|
Symbol: |
Mapk1tm2Melo |
Name: |
mitogen-activated protein kinase 1; targeted mutation 2, Sylvain Meloche |
MGI ID: |
MGI:4820400 |
Synonyms: |
Erk2flox |
Gene: |
Mapk1 Location: Chr16:16801246-16865317 bp, + strand Genetic Position: Chr16, 10.53 cM
|
Alliance: |
Mapk1tm2Melo page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:162580
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
Not Specified
|
|
Allele Type: |
|
Targeted (Conditional ready, No functional change) |
Mutation: |
|
Insertion
|
|
|
Mutation details: A loxP site was inserted upstream of exon 3. A floxed neomycin resistance cassette was inserted downstream of exon 3. Cre-mediated recombination removed the selection cassette and left exon 3 floxed.
(J:232897)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Mapk1 Mutation: |
41 strains or lines available
|
|
Original: |
J:162580 Voisin L, et al., Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation. Mol Cell Biol. 2010 Jun;30(12):2918-32 |
All: |
7 reference(s) |
|