Ivns1abp^tm1Htno
Targeted Allele Detail

Summary

• Symbol: Ivns1abp^tm1Htno
• Name: influenza virus NS1A binding protein; targeted mutation 1, Masahiko Hatano
• MGI ID: MGI:4820513
• Gene: Ivns1abp Location: Chr1:151220228-151240173 bp, + strand Genetic Position: Chr1, 64.06 cM
• Alliance: Ivns1abp^tm1Htno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162743
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 through 9 were replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on heart extracts. (J:162743)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ivns1abp Mutation: 22 strains or lines available

References

• Original: J:162743 Fujimura L, et al., Protective role of Nd1 in doxorubicin-induced cardiotoxicity. Cardiovasc Res. 2004 Nov 1;64(2):315-21
• All: 1 reference(s)