Tg(Fabp1-cre-GH1)1Jig
Transgene Detail

Summary

• Symbol: Tg(Fabp1-cre-GH1)1Jig
• Name: transgene insertion 1, Jeffrey I Gordon
• MGI ID: MGI:4820575
• Synonyms: Fabpl^{-596 to +21}Cre-hGH
• Transgene: Tg(Fabp1-cre-GH1)1Jig Location: unknown
• Alliance: Tg(Fabp1-cre-GH1)1Jig page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Fabp1-cre-GH1)1Jig expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Fabp1

• Mutation details: A 1.0 kb fragment encoding cre recombinase was placed between nucleotides -596 to +21 of the rat Fabp1 and nucleotides +3 to +2150 of the human growth hormone gene (hGH; GH1). The purified fragment and injected into FVB/N oocytes. RNase protection assays in 8-week old mice demonstrated cre mRNA expression levels in small intestine (high in proximal half, lower in distal portion) and cecum (moderate) with barely detectable levels in the colon. Expression was also detected in the liver. (J:65809)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fabp1 (species not specified) Summary of all recombinase alleles driven by Fabp1. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:65809 Wong MH, et al., Genetic mosaic analysis based on cre recombinase and navigated laser capture microdissection. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12601-6
• All: 1 reference(s)