Fzr1^Gt(3003)Tgen
Gene trapped Allele Detail

Summary

• Symbol: Fzr1^Gt(3003)Tgen
• Name: fizzy and cell division cycle 20 related 1; gene trap 3003, TransGenic
• MGI ID: MGI:4820747
• Synonyms: Cdh1^GT
• Gene: Fzr1 Location: Chr10:81202713-81214204 bp, - strand Genetic Position: Chr10, 39.72 cM
• Alliance: Fzr1^Gt(3003)Tgen page

Mutation origin

• Mutant Cell Line: 3003
• Germline Transmission: Earliest citation of germline transmission: J:162785
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pU-17 Vector Type: gene trap
• Mutation details: The gene trap vector, which contains (5' to 3') a lox71 site, a splice acceptor, the beta-geo cassette, a loxP site, a polyadenylation sequence, a lox2272 site, and a lox511 site, inserted between exons 1 and 2. (J:162785)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fzr1 Mutation: 43 strains or lines available

References

• Original: J:162785 Naoe H, et al., The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation. Mol Cell Biol. 2010 Aug;30(16):3994-4005
• All: 4 reference(s)