Kidins220^tm1.1Mvc
Targeted Allele Detail

Summary

• Symbol: Kidins220^tm1.1Mvc
• Name: kinase D-interacting substrate 220; targeted mutation 1.1, Moses V Chao
• MGI ID: MGI:4820793
• Gene: Kidins220 Location: Chr12:25024924-25113151 bp, + strand Genetic Position: Chr12, 8.54 cM
• Alliance: Kidins220^tm1.1Mvc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162839
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 14 and an FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 14. Cre mediated recombination removed exon 14 and the neo cassette. (J:162839)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kidins220 Mutation: 79 strains or lines available

References

• Original: J:162839 Wu SH, et al., Ankyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stability in vivo. Dev Neurobiol. 2009 Aug;69(9):547-57
• All: 4 reference(s)