Milr1^tm1Shib
Targeted Allele Detail

Summary

• Symbol: Milr1^tm1Shib
• Name: mast cell immunoglobulin like receptor 1; targeted mutation 1, Akira Shibuya
• MGI ID: MGI:4820795
• Gene: Milr1 Location: Chr11:106642052-106659620 bp, + strand Genetic Position: Chr11, 70.0 cM
• Alliance: Milr1^tm1Shib page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161854
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 1 was replaced by a neomycin resistance cassette. Absence of protein was confirmed by flow cytometry of bone marrow derived cultured mast cells. (J:161854)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Milr1 Mutation: 19 strains or lines available

References

• Original: J:161854 Hitomi K, et al., An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactions. Nat Immunol. 2010 Jul;11(7):601-7
• All: 6 reference(s)