Dynlt2a1^tm1June
Targeted Allele Detail

Summary

• Symbol: Dynlt2a1^tm1June
• Name: dynein light chain Tctex-type 2A1; targeted mutation 1, Juergen Neesen
• MGI ID: MGI:4820829
• Gene: Dynlt2a1 Location: Chr17:15247414-15261750 bp, - strand Genetic Position: Chr17, 8.95 cM
• Alliance: Dynlt2a1^tm1June page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162909
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was replaced with a neo cassette. (J:162909)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dynlt2a1 Mutation: 32 strains or lines available

References

• Original: J:162909 Rashid S, et al., Disruption of the murine dynein light chain gene Tcte3-3 results in asthenozoospermia. Reproduction. 2010 Jan;139(1):99-111
• All: 1 reference(s)