Epb41l2^tm1Note
Targeted Allele Detail

Summary

• Symbol: Epb41l2^tm1Note
• Name: erythrocyte membrane protein band 4.1 like 2; targeted mutation 1, Nobuo Terada
• MGI ID: MGI:4820843
• Synonyms: 4.1G^-
• Gene: Epb41l2 Location: Chr10:25235696-25399417 bp, + strand Genetic Position: Chr10, 12.26 cM
• Alliance: Epb41l2^tm1Note page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162881
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 and 2 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on Leydig extracts. (J:162881)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epb41l2 Mutation: 52 strains or lines available

References

• Original: J:162881 Terada N, et al., Involvement of a membrane skeletal protein, 4.1G, for Sertoli/germ cell interaction. Reproduction. 2010 May;139(5):883-92
• All: 4 reference(s)