Pklr^M1Neu
Chemically induced Allele Detail

Summary

• Symbol: Pklr^M1Neu
• Name: pyruvate kinase liver and red blood cell; mutation 1, Neuherberg
• MGI ID: MGI:4820881
• Synonyms: MUN, PK 10681
• Gene: Pklr Location: Chr3:89043449-89054091 bp, + strand Genetic Position: Chr3, 39.01 cM
• Alliance: Pklr^M1Neu page

Mutation origin

• Strain of Origin: (101/El x C3H/El)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• Mutation details: Heterozygotes have 160 per cent and homozygotes have 240 per cent of normal activity. Heat stability and electrophoretic mobility are unaffected.
• Inheritance: Codominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pklr Mutation: 25 strains or lines available

References

• Original: J:7771 Charles DJ, et al., A new pyruvate kinase mutation with hyperactivity in the mouse. Biochem Genet. 1984 Dec;22(11-12):1103-17
• All: 3 reference(s)