Dll1^m1Mhda
Chemically induced Allele Detail

Summary

• Symbol: Dll1^m1Mhda
• Name: delta like canonical Notch ligand 1; mutation 1, Martin Hrabe de Angelis
• MGI ID: MGI:4821259
• Synonyms: Dll1^C413Y
• Gene: Dll1 Location: Chr17:15587616-15597134 bp, - strand Genetic Position: Chr17, 8.95 cM
• Alliance: Dll1^m1Mhda page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a missense mutation in exon 8 that results in the amino acid substitution of tyrosine for cysteine at position 413. (J:150183)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dll1 Mutation: 46 strains or lines available

References

• Original: J:150183 Rubio-Aliaga I, et al., Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. PLoS One. 2009;4(6):e6054
• All: 2 reference(s)