Cacng7^tm1.1Mwa
Targeted Allele Detail

Summary

• Symbol: Cacng7^tm1.1Mwa
• Name: calcium channel, voltage-dependent, gamma subunit 7; targeted mutation 1.1, Masahiko Watanabe
• MGI ID: MGI:4821765
• Gene: Cacng7 Location: Chr7:3381471-3416737 bp, + strand Genetic Position: Chr7, 1.95 cM
• Alliance: Cacng7^tm1.1Mwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163029
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site and an frt flanked PGK-neomycin selection cassette were inserted 340 bp upstream of exon 2. A second loxP site was inserted 54 bp downstream of exon 3. Exons 2 and 3 were removed in mice by cre excision. (J:163029)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cacng7 Mutation: 53 strains or lines available

References

• Original: J:163029 Yamazaki M, et al., TARPs gamma-2 and gamma-7 are essential for AMPA receptor expression in the cerebellum. Eur J Neurosci. 2010 Jun;31(12):2204-20
• All: 1 reference(s)