Mks1^avc6
Chemically induced Allele Detail

Summary

• Symbol: Mks1^avc6
• Name: MKS transition zone complex subunit 1; atrioventricular canal 6
• MGI ID: MGI:4821832
• Gene: Mks1 Location: Chr11:87744041-87754629 bp, + strand Genetic Position: Chr11, 52.24 cM
• Alliance: Mks1^avc6 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: The causative mutation is a nonsense mutation, C-to-T transition at g.87853328. The C-to-T transition results in an arginine being converted to a premature stop codon, p.Arg27*. (J:237132)

Disease models

Expression

In Mice Carrying this Mutation:

3 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mks1 Mutation: 29 strains or lines available

References

• Original: J:163196 Kamp A, et al., Genome-wide identification of mouse congenital heart disease loci. Hum Mol Genet. 2010 Aug 15;19(16):3105-13
• All: 2 reference(s)