Tbx2^tm2.1Vmc
Targeted Allele Detail

Summary

• Symbol: Tbx2^tm2.1Vmc
• Name: T-box 2; targeted mutation 2.1, Vincent M Christoffels
• MGI ID: MGI:4822015
• Synonyms: Tbx2^fl
• Gene: Tbx2 Location: Chr11:85723441-85732774 bp, + strand Genetic Position: Chr11, 51.34 cM
• Alliance: Tbx2^tm2.1Vmc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163063
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A FRT flanked neo cassette with a 5' loxP site was inserted within intron 1 and an additional loxP site was inserted within intron 2 by homologous recombination. The selection cassette was removed by flpe mediated recombination. (J:163063)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx2 Mutation: 29 strains or lines available

References

• Original: J:163063 Wakker V, et al., Generation of mice with a conditional null allele for Tbx2. Genesis. 2010 Mar;48(3):195-9
• All: 6 reference(s)