Col4a1^ENU4004
Chemically induced Allele Detail

Summary

• Symbol: Col4a1^ENU4004
• Name: collagen, type IV, alpha 1; ENU mutation 4004
• MGI ID: MGI:4822148
• Synonyms: Col4a1^G394V
• Gene: Col4a1 Location: Chr8:11248423-11362826 bp, - strand Genetic Position: Chr8, 5.53 cM
• Alliance: Col4a1^ENU4004 page

Mutation origin

• Strain of Origin: DBA/2

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Male mice were exposed to 80 mg/kg body weight of ENU. This resulted in a G to T nucleotide substitution a position 1312 (NCBI accession # NM_009931) which caused a Glycine to Valine substitution at amino acid residue 394. (J:163225)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Col4a1 Mutation: 78 strains or lines available

References

• Original: J:63651 Favor J, et al., Saturation mutagenesis for dominant eye morphological defects in the mouse Mus musculus. Mamm Genome. 2000 Jul;11(7):520-5
• All: 7 reference(s)