Col4a2^ENU4003
Chemically induced Allele Detail

Summary

• Symbol: Col4a2^ENU4003
• Name: collagen, type IV, alpha 2; ENU mutation 4003
• MGI ID: MGI:4822172
• Gene: Col4a2 Location: Chr8:11362878-11499287 bp, + strand Genetic Position: Chr8, 5.62 cM
• Alliance: Col4a2^ENU4003 page

Mutation origin

• Strain of Origin: DBA/2

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Male mice were exposed to 80mg of ENU per kg of body weight. This resulted in a G to A nucleotide replacement at position 2073 (NCBI accession # NM_009932) and a glycine to aspartic acid substitution at amino acid residue 646. (J:163225)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Col4a2 Mutation: 74 strains or lines available

References

• Original: J:63651 Favor J, et al., Saturation mutagenesis for dominant eye morphological defects in the mouse Mus musculus. Mamm Genome. 2000 Jul;11(7):520-5
• All: 5 reference(s)