Iqsec1^tm1.1Hck
Targeted Allele Detail

Summary

• Symbol: Iqsec1^tm1.1Hck
• Name: IQ motif and Sec7 domain 1; targeted mutation 1.1, Hans-Christian Kornau
• MGI ID: MGI:4822241
• Synonyms: Iqsec1^fl
• Gene: Iqsec1 Location: Chr6:90636578-90965766 bp, - strand Genetic Position: Chr6, 40.16 cM
• Alliance: Iqsec1^tm1.1Hck page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163183
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 2 floxed. An FRT flanked neo cassette inserted downstream of exon 2 was removed by flp mediated recombination. (J:163183)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Iqsec1 Mutation: 43 strains or lines available

References

• Original: J:163183 Scholz R, et al., AMPA receptor signaling through BRAG2 and Arf6 critical for long-term synaptic depression. Neuron. 2010 Jun 10;66(5):768-80
• All: 3 reference(s)