N6amt1^tm1Gxu
Targeted Allele Detail

Summary

• Symbol: N6amt1^tm1Gxu
• Name: N-6 adenine-specific DNA methyltransferase 1 (putative); targeted mutation 1, Guo-Liang Xu
• MGI ID: MGI:4822324
• Gene: N6amt1 Location: Chr16:87151073-87165537 bp, + strand Genetic Position: Chr16, 49.52 cM, cytoband C3.3
• Alliance: N6amt1^tm1Gxu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163286
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 4 was replaced with a neo cassette. (J:163286)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any N6amt1 Mutation: 14 strains or lines available

References

• Original: J:163286 Liu P, et al., Deficiency in a glutamine-specific methyltransferase for release factor causes mouse embryonic lethality. Mol Cell Biol. 2010 Sep;30(17):4245-53
• All: 1 reference(s)