Ltb4r2^tm1Bodd
Targeted Allele Detail

Summary

• Symbol: Ltb4r2^tm1Bodd
• Name: leukotriene B4 receptor 2; targeted mutation 1, Bodduluri Haribabu
• MGI ID: MGI:4822400
• Gene: Ltb4r2 Location: Chr14:55998885-56002595 bp, + strand Genetic Position: Chr14, 28.19 cM, cytoband C1
• Alliance: Ltb4r2^tm1Bodd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163271
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A construct containing a fragment of the coding region, EGFP, and neo was inserted into the coding exon. The absence of transcript expression was confirmed by RT-PCR on bone marrow extracts. (J:163271)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ltb4r2 Mutation: 16 strains or lines available

References

• Original: J:163271 Mathis SP, et al., Nonredundant roles for leukotriene B(4) receptors BLT1 and BLT2 in inflammatory arthritis. J Immunol. 2010 Sep 1;185(5):3049-56
• All: 1 reference(s)