Fcrla^tm1.1Cln
Targeted Allele Detail

Summary

• Symbol: Fcrla^tm1.1Cln
• Name: Fc receptor-like A; targeted mutation 1.1, Marco Colonna
• MGI ID: MGI:4822412
• Gene: Fcrla Location: Chr1:170745163-170755169 bp, - strand Genetic Position: Chr1, 77.65 cM
• Alliance: Fcrla^tm1.1Cln page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163261
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3 and 4 were replaced with a floxed neo cassette. Cre mediated recombination removed the neo cassette. (J:163261)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fcrla Mutation: 19 strains or lines available

References

• Original: J:163261 Wilson TJ, et al., Fc receptor-like A associates with intracellular IgG and IgM but is dispensable for antigen-specific immune responses. J Immunol. 2010 Sep 1;185(5):2960-7
• All: 1 reference(s)