Capn9tm1Hiso
Targeted Allele Detail
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Symbol: |
Capn9tm1Hiso |
Name: |
calpain 9; targeted mutation 1, Hiroyuki Sorimachi |
MGI ID: |
MGI:4822423 |
Gene: |
Capn9 Location: Chr8:125302850-125345470 bp, + strand Genetic Position: Chr8, 72.81 cM, cytoband E2
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Alliance: |
Capn9tm1Hiso page
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Germline Transmission: |
Earliest citation of germline transmission:
J:163312
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Parent Cell Line: |
RENKA (ES Cell)
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Strain of Origin: |
C57BL/6N
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 3 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on gastric mucosa.
(J:163312)
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Key: |
hm |
homozygous |
ht |
heterozygous |
tg |
involves transgenes |
√ |
phenotype observed |
cn |
conditional genotype |
cx |
complex: > 1 genome feature |
ot |
other: hemizygous, indeterminate,... |
N |
normal phenotype |
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Genotype/ Background: |
| Allelic Composition | Genetic Background | Cell Line(s) |
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Loading... | | | involves: C57BL/6N | |
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Phenotypes: |
Affected Systems |
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digestive/alimentary system
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N
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digestive/alimentary phenotype
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N
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homeostasis/metabolism
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√
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increased susceptibility to injury
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√
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:163312 Hata S, et al., Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense. PLoS Genet. 2010;6(7):e1001040 |
All: |
4 reference(s) |
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