Fndc3b^tm1Maim
Targeted Allele Detail

Summary

• Symbol: Fndc3b^tm1Maim
• Name: fibronectin type III domain containing 3B; targeted mutation 1, Masayoshi Imagawa
• MGI ID: MGI:4822558
• Synonyms: fad104^-
• Gene: Fndc3b Location: Chr3:27470311-27765456 bp, - strand Genetic Position: Chr3, 10.91 cM
• Alliance: Fndc3b^tm1Maim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163660
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a neo cassette. The absence of transcript expression was confirmed by Q-PCR on mRNA from embryonic fibroblasts. (J:163660)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Fndc3b Mutation: 151 strains or lines available

References

• Original: J:163660 Nishizuka M, et al., Disruption of the novel gene fad104 causes rapid postnatal death and attenuation of cell proliferation, adhesion, spreading and migration. Exp Cell Res. 2009 Mar 10;315(5):809-19
• All: 4 reference(s)