Chdh^tm1Zei
Targeted Allele Detail

Summary

• Symbol: Chdh^tm1Zei
• Name: choline dehydrogenase; targeted mutation 1, Steven H Zeisel
• MGI ID: MGI:4822561
• Gene: Chdh Location: Chr14:29730957-29762423 bp, + strand Genetic Position: Chr14, 18.4 cM
• Alliance: Chdh^tm1Zei page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162343
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The exons 1-3 of the gene was replaced with a neo cassette by targeted homologous recombination. (J:162343)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Chdh Mutation: 37 strains or lines available

References

• Original: J:162343 Johnson AR, et al., Deletion of murine choline dehydrogenase results in diminished sperm motility. FASEB J. 2010 Aug;24(8):2752-61
• All: 2 reference(s)