About   Help   FAQ
Mir144/Mir451atm1.2Doca
Targeted Allele Detail
Summary
Symbol: Mir144/Mir451atm1.2Doca
Name: microRNA 451a; targeted mutation 1.2, Donal O'Carroll
MGI ID: MGI:4829618
Gene: Mir451a  Location: Chr11:77963996-77964067 bp, + strand  Genetic Position: Chr11, 46.74 cM
Alliance: Mir144/Mir451atm1.2Doca page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:163418
Parent Cell Line:  IB10/E14IB10 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion
 
Mutation detailsCre-mediated recombination removed the translation intiation site. The absence of either transcript was confirmed by northern blot analysis on bone marrow extracts. (J:163418)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mir451a Mutation:  4 strains or lines available
References
Original:  J:163418 Rasmussen KD, et al., The miR-144/451 locus is required for erythroid homeostasis. J Exp Med. 2010 Jul 5;207(7):1351-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory