Mir144/Mir451a^tm1.2Doca
Targeted Allele Detail

Summary

• Symbol: Mir144/Mir451a^tm1.2Doca
• Name: microRNA 451a; targeted mutation 1.2, Donal O'Carroll
• MGI ID: MGI:4829618
• Gene: Mir451a Location: Chr11:77963996-77964067 bp, + strand Genetic Position: Chr11, 46.74 cM
• Alliance: Mir144/Mir451a^tm1.2Doca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163418
• Parent Cell Line: IB10/E14IB10 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion
• Mutation details: Cre-mediated recombination removed the translation intiation site. The absence of either transcript was confirmed by northern blot analysis on bone marrow extracts. (J:163418)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mir451a Mutation: 4 strains or lines available

References

• Original: J:163418 Rasmussen KD, et al., The miR-144/451 locus is required for erythroid homeostasis. J Exp Med. 2010 Jul 5;207(7):1351-8
• All: 1 reference(s)