Tg(Col2a1-Glg1)#Brle
Transgene Detail

Summary

• Symbol: Tg(Col2a1-Glg1)#Brle
• Name: transgene insertion, Brendan Lee
• MGI ID: MGI:4829765
• Synonyms: Col2a1-Esl1
• Transgene: Tg(Col2a1-Glg1)#Brle Location: unknown
• Alliance: Tg(Col2a1-Glg1)#Brle page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Col2a1-Glg1)#Brle expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Glg1 (MGI:104967)

• Mutation details: The mouse promoter drives cartilage-specific expression of the mouse cDNA. No line name given (denoted by #). (J:163721)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:163721 Yang T, et al., E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta. J Clin Invest. 2010 Jul 1;120(7):2474-85
• All: 1 reference(s)