Tro^tm1Mfu
Targeted Allele Detail

Summary

• Symbol: Tro^tm1Mfu
• Name: trophinin; targeted mutation 1, Michiko N Fukuda
• MGI ID: MGI:4829800
• Gene: Tro Location: ChrX:149428300-149440579 bp, - strand Genetic Position: ChrX, 68.46 cM
• Alliance: Tro^tm1Mfu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163810
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An 0.8-kb PstI-BamHI fragment including the translation initiation site was replaced with a PGK-neo resistance cassette. Western blot analysis of mouse brain tissue lysates from wild-type and homozygous mutant mice showed that the encoded protein is not expressed. (J:163810)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tro Mutation: 27 strains or lines available

References

• Original: J:163810 Nadano D, et al., Significant differences between mouse and human trophinins are revealed by their expression patterns and targeted disruption of mouse trophinin gene. Biol Reprod. 2002 Feb;66(2):313-21
• All: 2 reference(s)