Tg(Sp7-cre/ERT2)#Hmk
Transgene Detail

Summary

• Symbol: Tg(Sp7-cre/ERT2)#Hmk
• Name: transgene insertion, Henry M Kronenberg
• MGI ID: MGI:4829803
• Synonyms: Osterix-CreERT2, Osx-CreERt
• Transgene: Tg(Sp7-cre/ERT2)#Hmk Location: unknown
• Alliance: Tg(Sp7-cre/ERT2)#Hmk page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Sp7-cre/ERT2)#Hmk expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Sp7

• Mutation details: The cDNA encoding a cre recombinase-ERT2 fusion protein along with a downstream polyA element was cloned into a BAC containing the Sp7 (Osx) promoter. Transgenic mice were generated. No founder lines were specified. (J:163667)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sp7 (species not specified) Summary of all recombinase alleles driven by Sp7. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:163667 Maes C, et al., Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels. Dev Cell. 2010 Aug 17;19(2):329-44
• All: 27 reference(s)