Cecr2^tm1.1Hemc
Targeted Allele Detail

Summary

• Symbol: Cecr2^tm1.1Hemc
• Name: CECR2, histone acetyl-lysine reader; targeted mutation 1.1, Heather E McDermid
• MGI ID: MGI:4829945
• Gene: Cecr2 Location: Chr6:120643330-120748151 bp, + strand Genetic Position: Chr6, 56.97 cM, cytoband D
• Alliance: Cecr2^tm1.1Hemc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163648
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 1 was floxed by homologous recombination. The exon was removed by cre mediate recombination. (J:163648)

Expression

In Mice Carrying this Mutation:	27 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cecr2 Mutation: 91 strains or lines available

References

• Original: J:163648 Fairbridge NA, et al., Cecr2 mutations causing exencephaly trigger misregulation of mesenchymal/ectodermal transcription factors. Birth Defects Res A Clin Mol Teratol. 2010 Aug;88(8):619-25
• All: 7 reference(s)