Entpd5^tm1Rre
Targeted Allele Detail

Summary

• Symbol: Entpd5^tm1Rre
• Name: ectonucleoside triphosphate diphosphohydrolase 5; targeted mutation 1, Robert Read
• MGI ID: MGI:4830114
• Gene: Entpd5 Location: Chr12:84420649-84455803 bp, - strand Genetic Position: Chr12, 39.18 cM, cytoband E
• Alliance: Entpd5^tm1Rre page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163795
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 7-10 were replaced by a LacZ neo cassette. (J:163795)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Entpd5 Mutation: 26 strains or lines available

References

• Original: J:163795 Read R, et al., Ectonucleoside triphosphate diphosphohydrolase type 5 (Entpd5)-deficient mice develop progressive hepatopathy, hepatocellular tumors, and spermatogenic arrest. Vet Pathol. 2009 May;46(3):491-504
• All: 1 reference(s)