Mcpt8tm1.1(HBEGF)Hkar
Targeted Allele Detail
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Symbol: |
Mcpt8tm1.1(HBEGF)Hkar |
Name: |
mast cell protease 8; targeted mutation 1.1, Hajime Karasuyama |
MGI ID: |
MGI:4830320 |
Synonyms: |
Mcpt8DTR, Mcpt8tm1.1(DTR)Hkar |
Gene: |
Mcpt8 Location: Chr14:56319623-56322730 bp, - strand Genetic Position: Chr14, 28.19 cM
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Alliance: |
Mcpt8tm1.1(HBEGF)Hkar page
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Germline Transmission: |
Earliest citation of germline transmission:
J:163761
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Mcpt8tm1.1(HBEGF)Hkar expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
HBEGF (1839) |
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Mutation details: A vector containing an IRES-human diphtheria toxin receptor (DTR) cDNA-EGFP and a floxed neo cassette was inserted downstream of exon 5. Cre mediated recombination removed the neo cassette. GFP expression is restricted to basophils.
(J:163761)
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Generation of the Mcpt8tm1.1(HBEGF)Hkar allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mcpt8 Mutation: |
26 strains or lines available
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Original: |
J:163761 Wada T, et al., Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks. J Clin Invest. 2010 Aug 2;120(8):2867-75 |
All: |
22 reference(s) |
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