Trim33^tm1.2Los
Targeted Allele Detail

Summary

• Symbol: Trim33^tm1.2Los
• Name: tripartite motif-containing 33; targeted mutation 1.2, Regine Losson
• MGI ID: MGI:4830323
• Synonyms: Ecto^-, Trim33^tm1.2Ros
• Gene: Trim33 Location: Chr3:103186609-103266086 bp, + strand Genetic Position: Chr3, 45.25 cM
• Alliance: Trim33^tm1.2Los page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163858
• Parent Cell Line: H1 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neo cassette was inserted into intron 1 and a third loxP site was inserted into intron 4 via homologous recombination. Cre mediated recombination removed exons 2 - 4 and the neo cassette. (J:163858)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim33 Mutation: 71 strains or lines available

References

• Original: J:163858 Morsut L, et al., Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo. Development. 2010 Aug 1;137(15):2571-8
• All: 2 reference(s)