Reck^tm1.1Noda
Targeted Allele Detail

Summary

• Symbol: Reck^tm1.1Noda
• Name: reversion-inducing-cysteine-rich protein with kazal motifs; targeted mutation 1.1, Makoto Noda
• MGI ID: MGI:4830337
• Synonyms: Reck^fl, Reck^flex2, Reck^L, Reck^Low, Rlow
• Gene: Reck Location: Chr4:43875530-43944806 bp, + strand Genetic Position: Chr4, 23.05 cM
• Alliance: Reck^tm1.1Noda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163845
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 2 was floxed. The FRT flanked neo cassette used for ES cell selection was removed by flp mediated recombination. (J:163845)

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Reck Mutation: 46 strains or lines available

References

• Original: J:163845 Chandana EP, et al., Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in mice. BMC Dev Biol. 2010;10:84
• All: 7 reference(s)