Ppp1r1b^tm5.1Pggd
Targeted Allele Detail

Summary

• Symbol: Ppp1r1b^tm5.1Pggd
• Name: protein phosphatase 1, regulatory inhibitor subunit 1B; targeted mutation 5.1, Paul Greengard
• MGI ID: MGI:4830458
• Synonyms: D32^fl
• Gene: Ppp1r1b Location: Chr11:98239232-98248622 bp, + strand Genetic Position: Chr11, 61.75 cM
• Alliance: Ppp1r1b^tm5.1Pggd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163700
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: LoxP sites were inserted surrounding exons 1-4 and a FRT flanked neomycin cassette was inserted between exon 4 and the 3' loxP site. The selection cassette was removed by flp-mediate recombination. (J:163700)

Generation of the Ppp1r1b^tm5.1Pggd allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp1r1b Mutation: 18 strains or lines available

References

• Original: J:163700 Bateup HS, et al., Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14845-50
• All: 3 reference(s)