Tg(Camk2a-Tardbp)#Ckjs
Transgene Detail

Summary

• Symbol: Tg(Camk2a-Tardbp)#Ckjs
• Name: transgene insertion, C K James Shen
• MGI ID: MGI:4830510
• Synonyms: CaMKII-TDP-43
• Transgene: Tg(Camk2a-Tardbp)#Ckjs Location: unknown
• Alliance: Tg(Camk2a-Tardbp)#Ckjs page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Camk2a-Tardbp)#Ckjs expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tardbp (MGI:2387629)

• Mutation details: The mouse promoter drives expression of the full-legth cDNA in the cortex and hippocampus. Three lines were generated (# denotes line number not specified). (J:163612)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:163612 Tsai KJ, et al., Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U. J Exp Med. 2010 Aug 2;207(8):1661-73
• All: 3 reference(s)