Arfgef2^{Gt(pMS1)16Wen}
Gene trapped Allele Detail

Summary

• Symbol: Arfgef2^{Gt(pMS1)16Wen}
• Name: ARF guanine nucleotide exchange factor 2; gene trap 16, Wolfgang Engel
• MGI ID: MGI:4833878
• Synonyms: line16
• Gene: Arfgef2 Location: Chr2:166647508-166739972 bp, + strand Genetic Position: Chr2, 87.22 cM
• Alliance: Arfgef2^{Gt(pMS1)16Wen} page

Mutation origin

• Mutant Cell Line: 2C98-16
• Germline Transmission: Earliest citation of germline transmission: J:164276
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion Vector: pMS1 Vector Type: gene trap
• Mutation details: Insertion of the gene trap vector occurred downstream of exon 7. LacZ reporter expression is detected in several developmental stages and in adult tissues. (J:135886, J:164276)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arfgef2 Mutation: 90 strains or lines available

Notes

Gene traps generated from the same library were created in 129/Sv cells.

Gene trap alleles generated in the screen described in J:135886 may have duplicate cell line ids. The original cell line ids were replaced with line designations. The mutant cell line id shown in the mutation origin section includes both the original id 2C98 and the line designation 16.

References

• Original: J:164276 Grzmil P, et al., Early embryonic lethality in gene trap mice with disruption of the Arfgef2 gene. Int J Dev Biol. 2010;54(8-9):1259-66
• All: 2 reference(s)