Tardbp^tm1.2Pcw
Targeted Allele Detail

Summary

• Symbol: Tardbp^tm1.2Pcw
• Name: TAR DNA binding protein; targeted mutation 1.2, Philip C Wong
• MGI ID: MGI:4834280
• Synonyms: Tardp^-
• Gene: Tardbp Location: Chr4:148696839-148711476 bp, - strand Genetic Position: Chr4, 78.77 cM
• Alliance: Tardbp^tm1.2Pcw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:164406
• Parent Cell Line: V26.2 (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 was deleted in the germline by interbreeding Tardbp^tm1.1 heterozygous animals with Tg(CAG-cre)13Miya mice. (J:164406)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tardbp Mutation: 68 strains or lines available

References

• Original: J:164406 Chiang PM, et al., Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16320-4
• All: 2 reference(s)