Nagpa^tm1Skor
Targeted Allele Detail

Summary

• Symbol: Nagpa^tm1Skor
• Name: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase; targeted mutation 1, Stuart Kornfeld
• MGI ID: MGI:4834497
• Gene: Nagpa Location: Chr16:5013153-5021876 bp, - strand Genetic Position: Chr16, 2.51 cM, cytoband A2
• Alliance: Nagpa^tm1Skor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:164482
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A beta-galactosidase-neomycin cassette was inserted between exons 4 and 8 by homologous recombination. (J:164482)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nagpa Mutation: 19 strains or lines available

References

• Original: J:164482 Boonen M, et al., Mice lacking mannose 6-phosphate uncovering enzyme activity have a milder phenotype than mice deficient for N-acetylglucosamine-1-phosphotransferase activity. Mol Biol Cell. 2009 Oct;20(20):4381-9
• All: 1 reference(s)