Nox3^het-5J
Spontaneous Allele Detail

Summary

• Symbol: Nox3^het-5J
• Name: NADPH oxidase 3; head tilt 5 Jackson
• MGI ID: MGI:4834516
• Gene: Nox3 Location: Chr17:3685515-3746536 bp, - strand Genetic Position: Chr17, 2.05 cM
• Alliance: Nox3^het-5J page

Mutation origin

• Strain of Origin: CBySmn.Cg-Prkdc^scid/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Duplication
• Nox3^het-5J involves 1 genes/genome features (Nox3) View all
• Mutation details: A 2173 base pair duplication that spans exon 11 results in a tandem duplication of the 147 base pair exon 11, which is predicted to result in an additional 49 in-frame amino acids of the NADPH binding domain. (J:169054)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nox3 Mutation: 38 strains or lines available

References

• Original: J:169054 Flaherty JP, et al., Molecular characterization of an allelic series of mutations in the mouse Nox3 gene. Mamm Genome. 2011 Apr;22(3-4):156-69
• All: 2 reference(s)