Tg(Msx2-cre/ERT)27Alj
Transgene Detail

Summary

• Symbol: Tg(Msx2-cre/ERT)27Alj
• Name: transgene insertion 27, Alexandra L Joyner
• MGI ID: MGI:4834769
• Synonyms: Msx2-CreER^T
• Transgene: Tg(Msx2-cre/ERT)27Alj Location: unknown
• Alliance: Tg(Msx2-cre/ERT)27Alj page

Transgene origin

• Strain of Origin: Swiss Webster

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Msx2-cre/ERT)27Alj expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Msx2

• Mutation details: A transgenic construct was generated that contained cre/ERT, beta-globin intron, LacZtag, and SV40polyA coding sequences under control of an apical ectodermal ridge (AER)-specific 520 bp Msx2 promoter. The purified construct was injected into Swiss Webster zygotes. Nine founders were generated with eight transmitting the transgene. Four expressed cre/ERT in the apical ectodermal ridge (AER). Studies were performed using one line (no. 27) that showed the strongest expression. (J:62572)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Msx2 (species not specified) Summary of all recombinase alleles driven by Msx2. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:62572 Kimmel RA, et al., Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. Genes Dev. 2000 Jun 1;14(11):1377-89
• All: 1 reference(s)