Clcf1^tm1Zou
Targeted Allele Detail

Summary

• Symbol: Clcf1^tm1Zou
• Name: cardiotrophin-like cytokine factor 1; targeted mutation 1, Xiaoming Zou
• MGI ID: MGI:4835025
• Synonyms: Cntf^tm1Zou
• Gene: Clcf1 Location: Chr19:4264479-4273548 bp, + strand Genetic Position: Chr19, 3.91 cM, cytoband A
• Alliance: Clcf1^tm1Zou page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:164637
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 2 and 3 were replaced with a neomycin selection cassette by homologous recombination. (J:164637)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clcf1 Mutation: 13 strains or lines available

References

• Original: J:164637 Zou X, et al., Neonatal death in mice lacking cardiotrophin-like cytokine is associated with multifocal neuronal hypoplasia. Vet Pathol. 2009 May;46(3):514-9
• All: 1 reference(s)