Smc1b^m1Ham
Spontaneous Allele Detail

Summary

• Symbol: Smc1b^m1Ham
• Name: structural maintenance of chromosomes 1B; mutation 1, Hamamatsu University School of Medicine
• MGI ID: MGI:4836167
• Synonyms: Smc1b^m1-Ham
• Gene: Smc1b Location: Chr15:84948890-85016158 bp, - strand Genetic Position: Chr15, 40.25 cM, cytoband E3
• Alliance: Smc1b^m1Ham page

Mutation origin

• Strain of Origin: ICR

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• A 16 bp deletion in exon 5 results in a frame-shift that generates a stop codon (TAA) at codon 247. (J:164958)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Smc1b Mutation: 69 strains or lines available

References

• Original: J:164958 Takabayashi S, et al., A spontaneous smc1b mutation causes cohesin protein dysfunction and sterility in mice. Exp Biol Med (Maywood). 2009 Aug;234(8):994-1001
• All: 1 reference(s)