Nlrp12^tm1Jpyt
Targeted Allele Detail

Summary

• Symbol: Nlrp12^tm1Jpyt
• Name: NLR family, pyrin domain containing 12; targeted mutation 1, Jenny P Y Ting
• MGI ID: MGI:4836357
• Gene: Nlrp12 Location: Chr7:3267458-3298370 bp, - strand Genetic Position: Chr7, 1.88 cM
• Alliance: Nlrp12^tm1Jpyt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:164725
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A region of exon 3 containing the Walker A and Walker B sequences was replaced by a neomycin resistance gene by homologous recombination. (J:164725)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlrp12 Mutation: 51 strains or lines available

References

• Original: J:164725 Arthur JC, et al., Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. J Immunol. 2010 Oct 15;185(8):4515-9
• All: 20 reference(s)