Paip2b^tm1.2Nso
Targeted Allele Detail

Summary

• Symbol: Paip2b^tm1.2Nso
• Name: poly(A) binding protein interacting protein 2B; targeted mutation 1.2, Nahum Sonenberg
• MGI ID: MGI:4837192
• Gene: Paip2b Location: Chr6:83783040-83808723 bp, - strand Genetic Position: Chr6, 35.97 cM
• Alliance: Paip2b^tm1.2Nso page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165272
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination of Paip2b^tm1.1 removes exon 3. The absence of protein expression was confirmed by western blot analysis on testes extracts. (J:165272)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Paip2b Mutation: 18 strains or lines available

References

• Original: J:165272 Yanagiya A, et al., The poly(A)-binding protein partner Paip2a controls translation during late spermiogenesis in mice. J Clin Invest. 2010 Sep 1;120(9):3389-400
• All: 3 reference(s)